DTIC ADA465827: New Model for Population-Subpopulation Differences

by: Defense Technical Information Center

Publication date: 2007-02-01

Topics: DTIC Archive, Crosier, Ronald B, EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR, *TOXICITY, *CHEMICAL WARFARE AGENTS, *NORMAL DISTRIBUTION, DEMOGRAPHY, RISK ANALYSIS, FACTOR ANALYSIS, TOXICOLOGY, DOSAGE,

Collection: dticarchive; additional_collections

Language: English

Civil defense planning requires estimates of the toxicity of chemical warfare agents to the general public, but the current toxicity estimates are for male soldiers. In ECBC-TR-224 and ECBC-TR-337, individual susceptibilities for both the general population and the military subpopulation were modeled by a lognormal distribution. The assumption of a lognormal distribution of individual susceptibilities for both the general population and a subpopulation cannot be correct. This report presents an alternative model and compares the previous and new models.