tomorrow and tomorrow night, and then things quiet down next week. >> for all of us here at nbc10, the news continues now with nbc nightly news with lester holt. have a great evening opinion tonight, feeling the heat. hillary clinton hunkers down as her team does damage control. new evidence that the e-mail investigation is taking a toll as new numbers reveal donald trump now closing in. pleading guilty. a stunning admission from the man whose life story so many came to follow as the face of subway. the dark secrets prosecutors say he's been hiding for years and what the company is saying tonight. desperate escape from isis. nbc news on the front lines of one of the biggest humanitarian crises in modern history. a harrowing mass exodus to get out alive. and targeting cancer. not by where it's located in your body. instead a whole new way of shrinking tumors. exciting results. you'll meet a woman who is living proof. "nightly news" begins

now. >> announcer: from nbc news world headquarters in new york, this is "nbc nightly news with lester holt." good evening. there is a fresh indication as we start tonight that hillary clinton's support among voters is eroding in the face of the scrutiny over e-mails she exchanged on a private server when she was secretary of state. while mrs. clinton remains the undisputed front-runner for the democratic nomination, new polling confirms a falloff both in the democratic race and in a match-up with gop front-runner donald trump. and it appears to be forcing some changes in her campaign. our political director chuck todd takes a closer look. >> reporter: on her first day of vacation in the hamptons hillary clinton is trying to take a few days off and celebrate president clinton's 69th birthday. but yet another poll today indicates that persistent questions about her handling of e-mails as secretary of state are taking a

political toll. she's now under 50% in a democratic primary. and that erosion of support is also showing up in a match-up with republican front-runner donald trump. clinton's nearly 25-point lead in late june is down to 6. believe it or not, today trump tried to play down his good poll numbers but still found time to take a shot at clinton. >> right now i have 16 other people that i'm looking at. and that's not my focus. but indirectly it probably is. and i think that hillary's going to have a hard time being in the election based on what's happening with the e-mails, the servers. maybe even the speeches. >> reporter: and he went on to twist the knife. >> her bigger problem is not the election. i think her bigger problem is going to be the criminal problem. >> reporter: tuesday clinton was put on the defensive over e-mails at a combative press conference. >> you were the official in charge. did you wipe the server? >> like, with a cloth or something? >> reporter: she was so dismissive of the controversy, as she left she said this. >> nobody talks to me about it other than you guys. >> reporter: later in an interview with

telemundo she repeated her basic defense. >> i never sent classified material. i never received anything marked classified. this will burn itself out. and it's being turned into a partisan attack. >> reporter: today clinton allies desperately tried to push back. mocking the criticism as old news. >> you know, these people, we don't like hillary, why is is that paul begala and james carville out there defending her? why can't we just attack her like we want to? and i understand that. i've been dealing with this for 23 years. >> reporter: but the campaign is mindful of the political damage this controversy is doing. they're on the air earlier than they ever planned with tv ads, including this new one today. look, lester, the campaign is trying to will this away as nothing but cheap partisan politics. but guess what? the calendar doesn't allow for them. mail issue to go away for her because she still has to testify before congress in october and the fbi is still determining whether there is a criminal probe to be had or not. so it will be a long fall. >> let's talk more about it, chuck.

thanks. donald trump says the controversy over hillary clinton's e-mails looks like water dwt on steroids. but the question a lot of people are asking is could she or anyone face criminal charges? we asked our justice correspondent pete williams to take a closer look. >> reporter: it's an issue that won't go away with a federal inquiry and members of congress demanding answers. what's the fbi investigating? federal agents are looking at whether classified information was compromised. they got that assignment after intelligence officials said some e-mails publicly released from her private server contain classified information like this one sent to her in november of 2012 about possible arrests in benghazi redacted in part before it was released. or this one sent by her close aide houma abedin on deteriorating conditions in benghazi. mrs. clinton says she didn't think any of those e-mails were classified. >> i did not send classified material, and i did not receive any material that was

marked or designated classified, which is the way you know whether something is. >> reporter: but o'could she be charged with a crime? could it be like the case against former general david petraeus? he pleaded guilty to mishandling classified information. clinton supporters say that was different. >> you had someone who knew he was holding on to classified information, admitted on tape that he knew the information was classified, and then took it and turned it over to someone who was not authorized to view that information. >> reporter: but a former republican attorney general says mrs. clinton could be charged just as petraeus was for keeping classified material where it shouldn't be. >> the place if his case was his home. in her case it's her private e-mail server. so the question then becomes whether she was the one who caused it to be done and whether she knew that information on there was classified. >> reporter: could others be charged with a crime? legal experts say that would take proof they knew they were putting classified material into her unclassified sevener or were grossly negligent in

doing it. faced with more e-mail questions today her campaign says nothing that has come to light suggests she did anything improper. pete williams, nbc news, washington. a stunning admission today from the man whose life story and struggle with his weight the country came to know was the long-time face of subway. prosecutors say there was a dark side to the company's now former pitchman jared fogle, who will plead guilty to disturbing charges including engaging in sexual conduct with minors. nbc's kevin tibbles reports. >> i'm jared the subway guy. >> reporter: today the man known to millions as the former face of the subway restaurant chain pleaded to child pornography and sex with minors charges and now awaits sentencing. >> this is about using wealth, status, and secrecy to illegally exploit children. >> reporter: 37-year-old jared fogle, a father of two, faces between 5 and 12 years behind bars. his lawyer spoke on the steps of the

courthouse. >> he expects to get well. he expects to continue to make amends to those people whose life he has affected. >> reporter: a month ago police raided fogle's suburban indianapolis home, seizing phones, laptops, and computers the authorities say contain tens of thousands of messages, images, and videos of child pornography. some made with hidden cameras. court documents say fogle got some images from the former director of fogle's non-profit, the jared foundation, established to teach kids about nutrition. and prosecutors say fogle on more than one occasion traveled to new york, where he had sex with minors. >> fame and fortune will not protect you from attacking those most vulnerable in our communities. >> reporter: for 15 years jared sold sandwiches, saying he'd lost more than 200 pounds eating at subway. the company suspended its relationship with him when the investigation was announced and today tweeted "jared fogle's

actions are inexcusable and do not represent our brand's values." his family also released a statement saying they are shocked and profoundly disappointed and very concerned for the well-being of those affected by his conduct. >> this is not about them as people but about others who chose to exploit them. so they're going to have a rough road ahead of them. >> reporter: as part of the plea deal something unusual, fogle will now pay $100,000 to each of his 14 victims. $1.4 million. meanwhile, his wife has announced that she is seeking a divorce solely, she says, for the sake of her children. lester? >> kevin tibbles tonight. thank you, kevin. there is late word tonight from fire officials that no one was killed in the huge explosion that leveled a motel near seattle. two people feared missing are now accounted for. but the blast is raising a lot of questions about how many other disasters like this are waiting to happen around the country. nbc's jacob rascon has more on that. >> reporter: they

might as well be scenes out of a war zone. buildings in pieces. an entire neighborhood obliterated. and the house next door. but bombs didn't destroy these american homes and businesses. each explosion started with a gas leak. last night in bremerton, washington -- >> my gut told me to and i'm glad it did. >> reporter: tonya heinz smelled gas and pulled the fire alarm at the motel 6 where she worked likely saving dozens of guests. the blast leveled a large section of the building, shocking the neighborhood and critically injuring a gas company worker. >> there is an element of russian roulette. these are very, very rare. just once in a while, though, when one of those leaks builds up underground or builds up in the basement of a building you get an accident like this. >> reporter: and like this one in new jersey. the home was empty when it suddenly blew up. some of the 300,000 miles of natural gas pipeline in the u.s. date back to the 1800s including the pipeline that erupted

underneath two apartment buildings in harlem last year, resulting in dozens of casualties. emergency officials say if you smell strong gas odor, see dead vegetation areas around pipeline or hear hissing from them get out of your home or workplace and call your local gas company. in washington the cause is not clear and authorities are investigating yet another pipeline accident that could have been a tragedy. jacob rascon, nbc news. in the west the destruction is mounting as dozens of new wildfires are sparking up every day. conditions on the ground remain explosive in this historic fire season, and tonight we're taking you right into the inferno. here's nbc news national correspondent miguel almaguer. >> reporter: in fire-scorched idaho nearly 400,000 acres lost so far. smoke jumpers are here. this a rare look at these elite fearless firefighters dropping into rugged terrain nearly impossible to reach by land.

20,000 pounds of cargo unloading. in oregon at least 36 homes destroyed. hundreds more threatened across the region. >> all they've got to do is drop a little match and poof. we're living in a tinderbox. >> reporter: in these conditions flames can spread at 30 miles an hour. california now reporting 200 to 300 new fires a week. in washington state 200 army soldiers got a crash course on fighting fires today. resources are strained, even after damon porter lost his home to a wildfire he stayed in the fight. crews showed us just how unforgiving the conditions are. >> pretty dangerous work up here. >> yeah. but it's what we train for. >> reporter: tonight that training put to the test. both day and night. miguel almaguer, nbc news, los angeles. there are new revelations tonight about inspections into iran's nuclear program as a fight rages in

congress there's word of a secret side deal by international investigators that would essentially allow iran to use its own inspectors at a suspected nuclear site. and that is raising red flags among republican lawmakers. our chief foreign affairs correspondent angela mitchell here with late details. >> reporter: tonight nbc news has confirmed that the u.n. inspection agency did agree to let iran inspect itself at one of its most sensitive military complexes parchin to clear up suspicion of past nuclear weapons activity there. but two senior officials tell me that u.n. inspectors will be on hand supervisoring the iranians at every step of the way. secretary of state kerry did brief congress in classified sessions about this secret arrangement. first reported today by the associated press. u.s. officials stressed this only relates to resolving suspicions of past nuclear activity. inspection of all future activity will be under much more rigorous rules. that said, this concession to iran is likely to help opponents as they try to kill the iran deal.

lester? >> andrea mitchell tonight. thank you. the brutality of isis and the ongoing war in syria have triggered an epic humanitarian crisis. the biggest wave of refugees in modern history. desperate men, women, and children by the tens of thousands, mostly from syria, fleeing in overcrowded boats, many drowning along the way. all hoping to reach the greek islands and safety. our own bill neely was there as they came ashore. >> reporter: they land with little but their dreams. they left everything behind. above all, war. their suffering clear. >> it was so hard. and we were dying. >> reporter: these syrians survived a crossing many done, and they're coming by the thousands. this is absolutely crammed. it's meant to hold 15 people. there must be 40 on this one. wave upon wave of refugees washing up on these shores. >> i'm very happy. i'm very happy. >> reporter: they are all newborn refugees,

part of the biggest migration in half a century, fleeing the terror group isis. >> they come to kill us. women. they -- >> reporter: your sister was killed. >> my daughter. >> i want to live. >> reporter: you want to live. tough men weep with relief. another boat crashes on shore. they are risking lives to escape. you can see how low this boat is in the water. and there's actually one man who's already out in the sea clinging to the side. they begin a long journey to richer countries like germany, but they face a long wait to be registered as refugees. and there have been clashes with police. food and water is scarce. frustration is not. >> if this is europe, we're going back to syria. >> reporter: but they keep coming, fleeing afghanistan too and the new threat there. isis or daesh.

>> nowadays daesh is coming up in afghanistan and it is huge. >> isis. >> yes, isis. >> greece at the end of a daily exodus without end. bill neely, lesbos. a new frontier in fighting cancer. doctors targeting tumors shrinking them in a whole new way with some pretty dramatic results keeping patients alive. we'll tell you more about that. also massive sinkholes opening up, one at the same place where a sinkhole killed a man sleeping in his bed. and a traffic nightmare today as a sinkhole suddenly nightmare today as a sinkhole suddenly ...and tkind of like you huffing sometimes, grandpa. well, when you have copd, it can be hard to breathe. it can be hard to get air out, which can make it hard to get air in. so i talked to my doctor. she said.. doctor: symbicort could help you breathe better, starting within 5 minutes. symbicort doesn't replace a rescue inhaler for sudden symptoms. symbicort helps provide significant improvement of your lung function. symbicort is for copd, including chronic bronchitis

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there is good news tonight in the battle against cancer. it's a whole new approach to treatment, a potential breakthrough that's showing a lot of promise in reducing the size of tumors in some patients when traditional chemotherapy just isn't working. nbc's anne thompson has the details. >> reporter: music is marianne anselmo's profession. ♪ love and refuge from cancer. the 59-year-old jazz vocalist has a brain cancer that kills most people in a year. but she's still singing nearly two years after her diagnosis because of a novel approach to treating cancers by their genetic mutation instead of where they start in the body. >> i was really putting my life in their hands. >> reporter: it meant taking a drug used for melanoma. and this is the result. >> everything you see in white here is her

tumor. and then over here you can see now nearly a year and a half later that white tumor is completely gone. >> so there's no cancer. >> we can't see any here. >> no evidence a tumor at all. >> you're kidding. >> yeah. >> really? >> it's true. >> reporter: a message dr. heimann gave marianne and her husband, joe. >> nothing. >> reporter: marianne is part of a new kind of clinical trial called the basket study where thousands of patients whose cancers have the same type of gene mutation are grouped together and treated with the same therapy even though they have different types of cancer such as lung, brain, or colon. >> with this type of approach we're starting to see responses in patients that we've never seen before with the use of traditional chemotherapy. >> reporter: in this trial using the melanoma drug, lung cancer and two rare cancer tumors were significantly reduced. but it did not work as well on coalo rectal cancer. there are caveats. it doesn't work for

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the danger may not be over from these massive explosions a week ago. a mysterious white foam has appeared in the streets as rain fell near the blast site in china, sparking fears that residual chemicals from the explosions may be causing it. some people who came into contact with the foam or rain reportedly experienced burning sensations on their skin and eyes. in florida a massive sinkhole has reopened at the very same place a man was killed in 2013 when the ground swallowed up his home. heavy rains are likely to blame. and near concord, new hampshire a sinkhole opened right in the middle of a highway, cathy a traffic nightmare when crews shut down that side of the interstate.

she was barbara gordon, the xlees commissioner's daughter by day and crime-fighting batgirl by night. yvonne craig has died. she rose to fame as a tough female sidekick to batman and robin on the 1960s hit tv series. she passed away at her home in los angeles of complications from breast cancer. yvonne craig was 78 years old. when we come back, under the sea. a natural wonder under the sea. a natural wonder that's disappearin i found her wandering miles from home. when the phone rang at 5am, i knew it was about mom. i see how hard it's been on her at work and i want to help. for the 5 million americans living with alzheimer's, and millions more who feel its effects. let's walk together to make an even bigger impact and end alzheimer's for good. find your walk near you at alz.org/walk. heart health's important... ...so you may... take an omega-3 supplement... ...but it's the ingredients inside that really matter for heart health.

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we're going to end tonight with an incredible journey under the sea which could be the closest many of us come to seeing an exotic underwater site facing a threat like never before. here's nbc's kerry sanders. >> reporter: hidden below the surface of the world's oceans, spectacular gardens of coral. and now documenting each stunning inch from australia to here in hawaii and beyond, divers with a one akind underwater camera, snapping a 360 degree picture every three seconds. the team partnered with google. so far stitching together more than 750,000 photos, creating a google street view of the world's coral reefs. we joined the team off

the eastern coast of oahu, where corals which may look like rocks are actually living animals facing what scientists fear could be extinction from what's called coral bleaching. >> this area here, it looks like it's got something on it. >> that's the bleached coral. and as you can see, this is the healthy coral. >> reporter: bleached corals turn white when they die. now because of el nino and warming conditions in the pacific ocean waters that should be in the high 70s are 84 degrees and could reach awn precedented 90 degrees, killing even more of the corals. >> you're talking an event similar to the rainforests of the world turning white over a very short period of time. everyone will be jumping up and taking notice, wondering what the hell is happening. but this is happening underwater on a massive scale. >> reporter: this new google view of the reef will be used to compare the coral's health in five years. today it's online, a

virtual dive of what has been out of sight, out of mind. until now. kerry sanders, nbc news, oahu. >> that will do it for us on this wednesday night. i'm lester holt. for all of us at nbc news, thank you for watching and good night. >> sandra bullock's mystery boyfriend. >> breaking news on her hook up and a surprise now on "extra". sandra bullock quietly

dating again. >> who she reportedly brought to jen and justin's wedding. >> plus megan fox and bryan austin green. >> are you ready to be a first lady? >> we're at home with mrs. trump in her sky high penthouse. five things you didn't know. >> subway jared's secret double life exposed today. his wife filing for divorce. >> matt dorn is here with the latest. >> we're there as there as jare federal court and what happened? >> looking for jared. >> rosie o'donnell on her missing daughter's safe return home. >> i'm glad she has been found. >> how a massive manhunt was finally solved through her cell phone. >> plus our favorite martian, matt damon. his mars and venus life at home >> now on extra from universal studios