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and our next guest says not to let your guard down just yet let's bring in mandy to help us break it down. great to have you with us as always to take us through a little bit of the sign posts that you are seeing. what exactly is the market telling you right now about what that next leg could be >> sure. hey, don it is great to be here what really stands out in the options market right now is not just that volatility is higher, which it is, but many of the other metrics are actually approaching the record high that we saw back last march during the depth of the pandemic selloff. for example, as you look at the cost of puts versus called, so a measure of demand for downside protection, that is nearing the record high that we saw last march, which is very surprising given that last march, vics was at 80. it's relatively much lower and obviously last march s&p had a much bigger selloff. in terms of what is driving that move, i would say three things obviously with the new variant omicron, you know, a lot of uncertainty regarding that but in addition, i would say the hawkish turn from th

africa were scientists 1st reported the variant, more employers and labor groups now say a vaccine mandy could help keep operations running. this bottle printing factory in johannesburg is one of many businesses struck down. after the discovery of omicron in africa's most developed economy. the rapid spread of the very end has led to a proliferation of infections and workplace absenteeism. a figure quite because we got all people the symptoms on others as the biggest way. but the people that will take the day off with that initial travel bands and government warnings to respect social distancing. after all, microns emergence, so shocked to the tourism and hospitality sectors of the economy. but now other companies like this hairdressing salon, are also feeling the pinch as the possibility of another hard lockdown looms large . at the start of south africa's main holiday period, corona dropped our business turnover by 60 percent. we are now gearing up for the festive season buying extra stock. another lockdown would result in us closing down our business. the south african government is c

oh okay, mandy. honda took a look at what he bought the shoot me gave him a gun with me from the al jazeera london broke off fantastic to people in thoughtful conversation with no host and no limitation. it leads as oppressive color. it was the struggle here. it would be much easier for me. it's might feel that white people, you have part to go into and sing a song, right? that again. so carry other people's way. is that in a minute you get way down. you got what you're doing and made one studio b unscripted on al jazeera from the world's most populated region in den and untold stories across asia and the pacific. to discover the current events with diverse coaches and conflicting politics. one 0, one east. on al jazeera, people have come to expect a lot from al jazeera over the years. it's, they're reporting the commitment to under reported places, the commitment to the human story. but it's also the idea often challenging dose and bower. if a politician comes on this channel, they will be challenge

oh, okay. mandy. hey, was jim mm. given that gun with me each and every one of us, it's about a responsibility to change our personal space for the better a. we could do this experiment and if by diversity could increase just a little bit and that wouldn't be worth doing. anybody had any idea that it would become a magnet, music could be rare species. they are asking for women to get 50 percent representation in the constituent assembly year. getting these people begun to collect the signature, a extremely important service that they provide to the city. why do we we need to take america to trying to bring people together trying to deal with people who left behind me. oh, can you hear me and tis the patient is realizing, excitement is growing as cattle a ways brings your favorite team to cut off for the fee for our upcoming 2021. greatness is in the air. late sore is one and to reach new heights. join us in cutoff from november, the 30th to december. the 18th booked your package now at canada. a ways don call oh not t

their symptoms were mandy bujold and they did not have to be hospitalized. yes. this person was aware of the news of omicron and that's why they appropriately reached out after they returned from travel and then had their positive test result through the color laboratory. they got their result and reached out to public health. so i really appreciate the person's awareness and collaboration on this case. >> yeah. there's another question here. yeah. i think that's probably an answer for dr. chiu. so the question is what lessons could sequencing provide for you. sequencing is very useful, has been shown to be very useful as a way to understand how understand the emergence of new variants in the community. it can also help with contact tracing, with being able to investigate outbreaks because the genome sequence is very often is specific for giving an individual so we can use the genomic sequence for how the transmission chains from person to person in the course of an outbreak. and from this example, it's useful in identifying specific variants such as the omicron

seeing some government considering a vaccine mandate, or even going so far as to institute of axing mandy. and for some people that goes with their profession. so if, say your health care worker, in some countries you choose not to be vaccinated, you risk losing your job. so that frustration people who believe the government should have that kind of reach, they're going out on the streets and making a very publicly known. so who exactly are these protest? this is a really varied group. there are lots of different social groups with very different core beliefs that are driving them out to these protests. so you've got the anti back scene group who doesn't believe that the vaccine is work or that they're unhealthy. you've got people who don't necessarily doubt the science of the vaccines, but they just for them, it's an issue of personal liberty. they don't think the government to tell them what to do. and then you've also got political groups extremist, political groups who are participating in these protests. germany's new interior minister says that some of these right wing groups are ac

can my best shad those g n n i k, mandy shad that's a half human beer. say it was couldn't had done my hadash her that a fee o'kelly's. moll thompson. in her left. phil comes his name. good. 2000. my little valet slend. be at the right in my fair bears, and he looked at the shadow. why then interrupted la la, look at in jama, fed they cannot father, a dirty raheem bus will firstly dad near with their live. but they thought power daily home with jeff to carlos did i say i missed him out. callous in missouri is a i thought baseline became melton piss me in. obey mod dully. and natalie hood derushia lula han is i shipped with better zillow lever height, like a rough monster of a dumb par, little mush 3rd of martin bessler and knew best still could. the 3rd may i kept my little bill now your credit in north america. melbourne. couldn't but that was mad that met b. jak interest on montana coming can a house club? well who comes to tell me? oh your talk stocks have 21 and we have which could owe us from an empty. when will it come from karen in limit a net and

africa where science is 1st reported the variant, more employers and labor groups now say a vaccine mandy could help keep operations running. this bottle printing factory in johannesburg is one of many businesses struck down after the discovery of omicron in africa's most developed economy. the rapid spread of the very end has led to a proliferation of infections and workplace absenteeism. your daughter is a figure why? because we got people not but they said they thought to fix off with initial travel bands and government warnings to respect social distancing. after all, microns emergence saw shocked to the tourism and hospitality sectors of the economy . but now other companies like this hair dressing salon, are also feeling the pinch as the possibility of another hard lockdown looms large . at the start of south africa's main holiday period, corona dropped our business turn over by 60 percent. we are now gearing up for the festive season buying extra stock. another lockdown would result in us closing down our business. the south african government is currently considering the idea of e

from behind the beat league leaders. chelsea. chelsea were a goal, but then they're cheaper. edward mandy was put in a horrible position by his defense. i made a terrible job of getting out of trouble with the family awarded a penalty which went well, lizzie, nice for to make it 11. just see, we're back in front before the break, thanks to mason mound, should on to 2nd goal and 2 games and well worth another look. i came last time again. geron bo, in with the why do this time? which is 3 minutes last arthur my, who want it for west town. sure whether it was a cross or a shot, but it went in to complete come back. and the forty's leak sporting ran out 31 winters over, been in the lisbon derby on friday. their opening goal from pablo was something a bit special sporting now level on points with porter. the top tennis. now we know about john, which is still keeping quiet on whether he'll defend his title at next month. australian open. his participation is in doubt because all players have to be vaccinated against co 19 to compete. well, number one has so far, refused to say if he's had the

has seen more than a week of intense fighting between the men mom in korea national union for bud. mandy has mall these fighters from the current national defense organization or k n d o. it's one of 2 ethnic fighting groups operating on the border between thailand, amanda, and for the past week, it's been involved in fierce fighting with government forces. made a general note on the air is leading his units on patrol new. the current state help post to strengthening unify local forces. i think the main reason they're dropping bombs at night is to terrorize the people and also to encourage or to encourage their troops by saying ok we, we, we are behind new. right. and are we trying to talk with all the current on group to unify themselves and to fight against the the worst enemy that we're, that we're facing right now who who many flight of thought here the k into had quarters. it's early morning in this remote village. you recruits a quote out for roll call and this tiny arrive just days ago along with fighters from the korean national union or k and you that's off. they fled military a

we're goal lot for that poor, bad have but there, keeper edward, mandy, under pressure. and he made a terrible job of getting out of trouble giving away a penalty and the process well as any steps up for west ham and for to make it one. all. chelsea, we're back in front for the break. thanks to a volley from mason, mount about submit fielders, 2nd goal and as many games back. it came west ham again. jerrod bowen with the wiser this time and with just 3 minutes. slap arthur my sooner who won it for went down. lucky. liverpool, the chance to briefly go top. it looked like they would miss out and 4 deep to injury time again. well, manager, happy man. so those 3 score you just seem to keep going and that's what we did. and yeah, and dba regi, debt legend came and finished enough for us a lot. but after all that at manchester city who have ended up top of the table, he sterling for the 99 primary legal and his career. fernando silva got the other 2 and a 31 when city. one point clear labor for chelsea flipped a 3rd of arthur and i suffered their 1st loss under the leadership

women's football, because it would be the same year as women's football either sports olympic games or mandy mistake, it's simply a bad idea. and it will not happen because it's a bad idea, not because we are opposing or manchester city or 8 point clean out the top of the english premier league equity oversight beating breakfast. john mail to y and wednesday, in the international far deny getting the only goal of the game. it was city center league when in iraq. chelsea and in liverpool are more than exceptional. one is a champion for new robin. the liverpool had been our big arrival in dallas through 4 years and, and yet the distance because not because the drop point is because we wanna take him to neural regardless of what pap says, it was a bad night for cities title arrivals. chelsea that he took the lead against brighton at stamford bridge from luda khaki with that goal. but sir danny wellburn scored an injury time equalize the game. finishing won won despite dropping points . chelsea did move up the 2nd in the table just ahead of liverpool. now brooklyn that's play carry irving has be

mr. mandy, can you tell us 1st, specifically this launch into space? was it part of the ballistic missile program, or is it part of the space program? are they very separate or intertwined? and also can you tell us why with the iranians decide to do this at this juncture? it's a part of the iran space program, and iran had a space program for quite a long time. it's spent satellites into orbit on a number of occasions. it's over 10 years since iran incentives for a satellite into space. i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to it's based program or even it's miss out ballistic missile technology we saw runs military maneuvers just carried out a few days ago. that was obviously a message the united states into this railey, that any military conflict would need to devastating consequences. in other words, those maneuvers were carried out to prevent war. but when the iranians believe that when the united states is trying to prevent iran from importing even medicine, and when the euro

i'm joined now by mohammed mirandi and mr. mandy, can you tell us 1st, this, specifically, this launch into space? was it part of the rods? ballistic missile program were, is a part of the space program, or they very much to separate or intertwined. and also can you tell us why with the iranians decide to do this at this juncture? it's a part of iran space program, and iran had a space program for quite a long time. it's sent satellites into orbit on a number of occasions. it's over 10 years since iraq incentives for a satellite into space. i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to its space program or even it's missile. ballistic missile technology. we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this railways that any military conflict would lead to devastating consequences. in other words, those maneuvers were carried out to prevent war. but to win the run is believed that when the united states is trying to prevent iran from importing even me

i'm joined now by mohammed mirandi and mr. mandy, can you tell us 1st, this, specifically, this launch into space? was it part of the rods? ballistic missile program were, is a part of the space program. are they very much to separate or intertwined? and also can you tell us why with the iranians decide to do this at this juncture? it's a part of iran space program, and iran had a space program for quite a long time. it's cent. satellites into orbit on a number of occasions is over 10 years since iran sent its 1st satellite into space . i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to its space program or even it's missile. ballistic missile technology, we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this railways that any military conflict would lead to the devastating consequences. in other words, those maneuvers were carried out to prevent war. but to win the run is believed that when the united states is trying to prevent iran from importing even me

mr. mandy, can you tell us 1st, specifically this launch into space? was it part of the ballistic missile program, or is it part of the space program? are they very separate or intertwined? and also can you tell us why with the iranians decide to do this at this juncture? it's a part of the iran space program, and iran had a space program for quite a long time. it's spent satellites into orbit on a number of occasions. it's over 10 years since iran incentives for a satellite into space. i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to its space program or even it's missile. ballistic missile technology. we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this railways that any military conflict would lead to devastating consequences. in other words, those maneuvers were carried out to prevent war. but when the right is believed that when the united states is trying to prevent iran from importing even medicine, and when the

of what we can call the reaction and it's a reaction not only to deal with maximum pressure as mr. mandy. just mention what's also and more importantly, i think to the recent wave of xander several times attacks against it's. so basically, i mean, honestly speaking, i think they can see behind the development on the ground that the more israel tries to kind of slow down the runs program, the more unions are determined to develop their new programs. so this has been one of the main issues behind this development, which is what on the other hand, in terms of calculation, of course, a very important part, a calculation. it is, has been to use it as a leverage because just imagine a situation after this for maximum, british or i'm imposing sanctions against you. if you don't want to answer them, your shane taylor without any are actually in the, in the position that it was before trumps with all of it's would be in a review position. so that was, i think, one of the main reason that it started in the 1st place to launch its nuclear activity. so the combination of these 2 factors have kind of

and it's a reaction not only to deal with maximum pressure as mr. mandy, just mention what's also and more importantly, i think, to the recent, very, very xander sabotage tax against its nuclear. so basically, i mean, honestly speaking they can see the developments on the ground at the more israel tries to kind of slow down the runs program. the more unions are determined to develop their new programs. so this has been one of the main issues behind this development, which is what, on the other hand, in terms of calculation, of course, a very important part of the reason i'm trying to ration it's has been to use it as a leverage because just imagine a suspicion after this for maximum pressure and imposing sanctions. i guess you don't. if you don't want to go sankey without any actually in the, in the position that it was before with all of its would be in a very nice position. so that was, i think, one of the main reason that started in the 1st place to advance it's nuclear activities. so the combination of these 2 factors have kind of let us to the situation that we are now. i'm a bra

i'm joined now by mohammed mirandi and mr. mandy, can you tell us 1st, this, specifically, this launch into space? was it part of the rods? ballistic missile program were, is a part of the space for grammar. they very much to separate or intertwined. and also can you tell us why with the iranians decide to do this at this juncture? it's a part of iran space program, and iran had a space program for quite a long time. it's cent. satellites into orbit on a number of occasions is over 10 years since iraq incentives for a satellite into space. i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to its space program or even it's missile. ballistic missile technology, we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this railways that any military conflict would lead to the devastating consequences. in other words, those maneuvers were carried out to prevent war. but to win the run is believed that when the united states is trying to prevent iran from importing even

the premier league ordeal is mandy was at home for him. sterling or a spec and have penalty for a one year old victory o. a penalty also decided liverpool game against aston villa mohammed sala was brought down in the penalty area and then he made no mistake from the spot with the red for main one points behind city, troy. all that fit for me. but before we go, a quick recap of our top stories. algeria faced host katara in the semi finals of the arab, after securing a win against their north african neighbor, morocco, and fevers. secretary generals is much more i says she's looking forward to working with newly elected camry, indian f, a president samuel echo we'll have the results have the formula one title decider and more in sports at 1545, g m t. stay with us here on al jazeera. after the break. we have another new updates with and less than a year. capital will host the middle east 1st. well, in preparation the country is stage in a major settlement with 16 nations going head to head in thanks purpose bill stadiums for 2022 will keep

of what we can call the reaction and it's a reaction not only to deal with maximum pressure as mr. mandy just mention what's also and more importantly, i think, to the recent, very, very xander, sabotage attacks against you. so basically, i mean, honestly speaking, i think they can see the development on the ground that the more israel tries to kind of slow down on smoking program, the more unions are determined to develop their new programs. so this has been, one of the main issue is behind this development, which is what on the other hand, in terms of calculation, of course, a very important part, a calculation. it is, has been to use it as a leverage because just imagine assertion. after this whole maximum of british or i'm imposing sanctions against you, if you don't wanna to concert in your shank table without any are actually in the, in the position that it was before trumps with all of it's would be in a review position. so that was, i think, one of the main reason that it started in the 1st place to launch its nuclear activity. so the combination of these 2 factors have kind of l

our hardest hit with the situation is described as life threatening nor burn mandy reports. this is the moment a huge fire came rolling down the foothills of boulder, county and colorado. the false moving blaze engulfed hundreds of homes. local say they haven't experienced anything like it. you know, this is the 1st time i've really been involved in anything like this and i'll tell you it is really scary and things in the trees. oh, they're all up and flames like there's embers everywhere. so it makes me very frightened, of course, with the wind. it's going to continue to spread to other homes, strong winds, and dry conditions of fueling the flames. if this will say, some of the fires was sparked by falling power lines, which it nighted prairie grosses estates were emergencies being declared and tens of thousands of people evacuated from the towns of superior and louis. phil. many getting stuck in traffic jams as they tried to scape gusts of a 100110 miles an hour's can and have moved this fire down a football field in a matter of seconds. very little time to get out very li

i think this needs to go back down progress. mandy, for 3 reasons. the 1st season is that really 5 insisted on discussing going. the economy shows and security issues avoiding all possibilities of a political process that would lead to ending occupation and upper teens are subjected to and that means they are going to diminish seconds. this meeting is happening while the very last 2nd of violence against the palestinian population and the same work of several announcements by the head of this government ministers that there is no place in states. no political process said this meeting is happening with the minister of a army and that means drinking down delivery of the relationship between the 2 sides. and it makes the relationship as if it's not ok via i'm done occupied. and there is no equality in this process. finally, i think this meeting has increased the in term of the most interesting in groups have objected to this meeting, mainly because they see it as and it's really trapped to bring palestinians into that trap, which is nothing but the imp

laura burton, mandy reports, people barely walk in the deployment of troops and tanks. many want an end to file, and it's beset ethan democratic republic of congo for decades. a joint forces operation by the u. canden and complete governments, and through townsley allied democratic forces. the rebel group is accused of massacring thousands of people. at this, we support this operation and the collaboration between our 2 presidents to put an end to the adf killers. we're expecting a lot from this operation because we want to resume with our normal life. this is a, it's a real joy for us to see the u. p. d. f. soldiers. finally conducting military operation and d, see mainland benny region. it was our demand and the suffering of the people in binion did treated regions who have long been massacred by the adf. you can the government plainfield idea for november suicide bombings in kampala. the comalies army have been fighting rebels for years and introduce martial law in the region. 6 months ago. we decide to bring together our digital services. and now we bring together a

this kind of what we can call the reaction and it's a reaction not only to us maximum pressure, as mr. mandy just mention what's also and more importantly, i think, to the recent, very, very xander several times attacks against it's. so basically, i mean, honestly speaking, i think they can see the development on the ground at the more israel tries to kind of slow down your own smoking program, the more your renewals are determined to develop their new programs. so this has been one of the main issues behind what on the other hand, in terms of calculation, of course, a very important part, a calculation. it has been to use it as a leverage because just imagine assertion. after this whole maximum of british or angry, imposing sanctions against you, if you don't want it to concert in your shank table without any are actually in the, in the position that it was before with all of it's would be in a review position. so that was, i think, one of the main reason that it started in the 1st place to launch its nuclear activity. so the combination of useful factors have kind of led us to the situatio

i'm joined now by mohammed mirandi and mr. mandy, can you tell us 1st, this, specifically, this launch into space? was it part of the rods ballistic missile program were? is it part of the space program? are they very much to separate or intertwined? and also can you tell us why with the iranians decide to do this at this juncture? it's a part of iran space program, and iran had a space program for quite a long time. it's cent. satellites into orbit, on a number of occasions is over 10 years since iran sent its 1st satellite into space . i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to its space program or even it's missile. ballistic missile technology. we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this railways that any military conflict would lead to the devastating consequences. in other words, those maneuvers were carried out to prevent war. but to win the run is believed that when the united states is trying to prevent iran from importing even m

multiple articles and complex challenges of the most important task is to help africa understand. mitigate mandy type in crisis, the soonest on to stabilize unrestored, the economy will hold in the u. s. insisted the un emergency relief coordinator report back to the counsel every 6 months to ensure the aid does not benefit those on the sanctions list. it is essential for the security council to receive regular updates on the implementation of this resolution. such information is critical to enabling sufficient oversight to ensure that assistance is reaching the intended beneficiaries. by mitigating diversion, after the resolution passed, a spokesman for the taliban, welcome the measure saying we appreciate it. it can help afghanistan's economic situation. he also called on the international community to speed up the removal of crippling economic sanctions. the u. n. has warned that half the population doesn't have enough to eat. cash flow has been an issue since the taliban took control of the government, leading the world bank to freeze nearly $10000000000.00 and assets. civil servants haven't

mr. mandy, can you tell us 1st, specifically this launch into space? was it part of the rounds of ballistic missile program, or is it part of the space program? are they very much the separate? are intertwined. and also can you tell us why with the iranians decide to do this at this juncture? it's a part of the iran space program, and iran had a space program for quite a long time. it's cent satellites, into orbit on a number of occasions. it's over years since iran sent its 1st satellites into space. i think it's pretty clear that the iranians are going to continue with business as usual, whether it's regards to it's space program or even it's missile. ballistic missile technology. we saw iran's military maneuvers just carried out a few days ago. that was obviously a message the united states into this rallies that any military conflict would lead to devastating consequences. in other words, those maneuvers were carried out to prevent war. but when the writing is believed that when the united states is trying to prevent iran from importing even medici

that mandy be true. molly: let's talk about voters and inflation. that is something voters care about. 84 percent. here we are on the cusp of a new year talking about the midterms. how big of an impact on that issue be for democrats? >> it will be huge. republicans will talk about it all the time. we have a record of president biden saying don't worry. the inflation is transitory. it will go away. that was months and months ago. and has not gone away it has gotten worse. and what we have seen in the latest foxhole is a plurality of americans believe that president biden's policies specifically are making the inflation problem worse. it's a huge political opportunity as the midterms are coming up and it is a real liability for democrats. molly: thank you very much we appreciate your time and we will be back. ow! i'm ok! only pay for what you need. ♪ liberty. liberty. liberty. liberty. ♪ only in theaters december 17th. >> man: what's my safelite story? ♪ liberty. liberty. liberty. liberty. ♪ my truck...is my livelihood. so when my windshield c

mandy patinkin i know from "criminal minds." >> can you say it one more time? >> inconceivable. >> love it. perfect. >> nailed it. >>> coming up, our fashion forecast. melissa garcia has the top trends in 2022. ♪ all this is elodia. she's a recording artist. 1 of 10 million people that comcast has connected to affordable internet in the last 10 years. and this is emmanuel, a future recording artist, and one of the millions of students we're connecting throughout the next 10. through projectup, comcast is committing $1 billion so millions more students, past... and present, can continue to get the tools they need to build a future of unlimited possibilities. ♪ i got you ♪ >>> we are back now on "gma" morning we're talking fashion. thankfully we have our very own fashion forecaster with us right now, lifestyle expert melissa garcia is going to tell us what trends are on the horizon. melissa, thank you so much for being here. happy new year's eve to you. >> thank you, happy new year to you too. >> of course, i know. when you look to next year in terms of fas

mandy joining us now. there are bus stop -- bunch of questions. how would this work? what would be the impact? i thought we were short on trips around the world. is this going to make it worse? >> i do not think it helps alleviate the supply shortages we have seen when it comes to the chips. when i look at the chinese contribution, especially to the foundry side of things where smic falls, to smc is still the leading player. tsmc and umc, those are based out of thailand. that is where the likes of apple, nvidia, they rely on these foundry's to manufacture most of their chips. in the case of china, they have some capabilities to process or manufacture chips, not really at the leading edge. that is why i feel sanctioning smic will not be a big deal for the chip companies like nvidia or apple. alix: is there one company or one area where it actually could hurt that we need to focus on right now? mandeep: again, in the case of smic, they probably do more trailing chips. it could help on the auto side. i did not know the exact exposure. i think we are in that environment w

their symptoms were mandy bujold and they did not have to be hospitalized. yes. this person was aware of the news of omicron and that's why they appropriately reached out after they returned from travel and then had their positive test result through the color laboratory. they got their result and reached out to public health. so i really appreciate the person's awareness and collaboration on this case. >> yeah. there's another question here. yeah. i think that's probably an answer for dr. chiu. so the question is what lessons could sequencing provide for you. sequencing is very useful, has been shown to be very useful as a way to understand how understand the emergence of new variants in the community. it can also help with contact tracing, with being able to investigate outbreaks because the genome sequence is very often is specific for giving an individual so we can use the genomic sequence for how the transmission chains from person to person in the course of an outbreak. and from this example, it's useful in identifying specific variants such as the omicron

i couldn't sing like mandy patinkin. i couldn't compose like sondheim. but that play was a window from this world to that, and i will always be grateful to you for laying out the desire and the beauty of the act of creation itself, regardless of where that may take you." >> when i read that, i was touched. and i'm touched again. thank you. ( applause ) >> stephen: thank you. now, broadway fully opened this ek ic fantastic. >> yeah, isn't that great? >> stephen: which is fantastic. and soon "company," your musical "company," is coming back in november, this time swapping the gender of male-female of bobbie and other members of the cast. have you seen it yet? >> oh, yeah, i saw it in london. and, also, we had a week of previews here before the pandemic closed everything down. so i saw it there. it's a wonderful production. highly recommended. and i don't usually tout my own stuff, but i urge everybody here to see it. ( laughter ) ( cheers and applause ) >> stephen: i have a date with christine buransky. she's taking me. she asked me to go with her. >> you'

here's cnbc's kate rog sneers like many gym owners, mandy silk is banking on the new year and its resolutions to bolster business at her franchise in pittsburgh but the anti-masking and vaccinations are looming large over operations. >> everyone has their own sperm standard and their own threshold in the pandemic. it's been very personal. >> reporter: she's not mandated by the state to have the patrons show their vaccination status or vaccination card in class and she asks those not vaccinated mask up and those sick or exposed must be tested >> every day i ask myself am i doing enough should i be doing more, and if i am doing more, am i alienating somebody it's really hard to know what to root for. >> it's a challenge operators are facing across the country at cities and cities who implement varying regular laces and the omicron variant surges some have taken it upon themselves to enforce masks and vaccines while others are giving them the right to choose, even defying mandates. >> i'm a firm believer it's not my responsibility nor is it my job to tell people what to do tore give me certain i

their symptoms were mandy bujold and they did not have to be hospitalized. yes. this person was aware of the news of omicron and that's why they appropriately reached out after they returned from travel and then had their positive test result through the color laboratory. they got their result and reached out to public health. so i really appreciate the person's awareness and collaboration on this case. >> yeah. there's another question here. yeah. i think that's probably an answer for dr. chiu. so the question is what lessons could sequencing provide for you. sequencing is very useful, has been shown to be very useful as a way to understand how understand the emergence of new variants in the community. it can also help with contact tracing, with being able to investigate outbreaks because the genome sequence is very often is specific for giving an individual so we can use the genomic sequence for how the transmission chains from person to person in the course of an outbreak. and from this example, it's useful in identifying specific variants such as the omicron

every 2 days, and you only need a pocket calculator to see that that 6 you dream les fast in this is mandy mitchell . while vaccines are the 1st line of defense, germany's government is preparing new restrictions for as early as next week, even for the fully vaccinated like to so last night. by to that we will have further restrictions on private contacts. so we're well prepared for the spread of the new virus mutation all over europe. was them all her to cuba, novel falsified to what the new curbs will look like. is unclear. the government is discussing possible measures with the leaders of germany, states, if case numbers saw they could be tough, is global when these predict weather, if experts, predictions are confirmed and what we're seeing in neighboring countries continues be allied, and we can't rule out a general lockdown including everything from businesses to education, to private gatherings after yet mismatch reason. for starters, that a likely mean large new year's eve parties will be canceled. and those making fitness resolutions for 2022 might need to postpone hitting the gym

why don't they talk about what that mandy? thank you. host: your top foreign-policy story of 2021. as we show you from last week, anthony boykin's end-of-the-year news conference talking about his work and the work of the state department over the past 12 months. >> when i walked into the state department, my first day as secretary, we had 19 lockdowns around the world. at 1% of the united states was vaccinated compared to more than 60% today. we were dealing with the worst economic crisis of the great depression. the crisis has accelerated. our relationships with our partners were strained. many questioned whether america would or even could lead again. a few guiding premises this year one is that american engagement american leadership matters. the word -- the world doesn't organize itself. we are not engaged, or we don't lead, one of two things happen. either some other country tries to take our place, but not the way that advances our interests and values. or no one does. and then you get chaos. either way, it doesn't serve the american people. another ms is finding new ways to

their symptoms were mandy bujold and they did not have to be hospitalized. yes. this person was aware of the news of omicron and that's why they appropriately reached out after they returned from travel and then had their positive test result through the color laboratory. they got their result and reached out to public health. so i really appreciate the person's awareness and collaboration on this case. >> yeah. there's another question here. yeah. i think that's probably an answer for dr. chiu. so the question is what lessons could sequencing provide for you. sequencing is very useful, has been shown to be very useful as a way to understand how understand the emergence of new variants in the community. it can also help with contact tracing, with being able to investigate outbreaks because the genome sequence is very often is specific for giving an individual so we can use the genomic sequence for how the transmission chains from person to person in the course of an outbreak. and from this example, it's useful in identifying specific variants such as the omicron

la actriz mandy moore esta honrando a su padre quien acaba realizar su Último viaje como piloto de american airlines ayer, la actriz publicÓ una foto es el final de una era para nuestra familia, despuÉs de cruenta y dos aÑos en la empresa ha alcanzado la edad de jubilaciÓn obligatoria y se estÁ despidiendo de una carrera que siempre ha dicho que se siente mÁs como un pasatiempo, espero que estÉs orgulloso or que nosotros estamos celebrando. >> felicidades al seÑor. >> te imaginas encontrar serÁn este vuelo? raÚl: los chicos o noticioso de la maÑana. satcha: que lindo. alan: vamos al espacio. porque la nasa revela sus 10 nuevos candidatos a astronautas y la 10 nuevas personas que intentarÁn eso, conquistar el espacio. karla: entre ellos hay un puertorriqueÑo que se descata entre mÁs de 12,000 solicitantes. satcha: cuentas desde revela lo que representa este gran logro y lo que sigue de ahora en adelante. astrid: marcos de 37 aÑos es un piloto de las fuerzas aÉreas que fue elegido como uno de los 10 nuevos candidatos a astronauta de la nasa. mÁs de 12,000 solicitantes para tr

why don't they talk about what that mandy? thank you. host: your top foreign-policy story of 2021. as we show you from last week, anthony boykin's end-of-the-year news conference talking about his work and the work of the state department over the past 12 months. >> when i walked into the state department, my first day as secretary, we had 19 lockdowns around the world. at 1% of the united states was vaccinated compared to more than 60% today. we were dealing with the worst economic crisis of the great depression. the crisis has accelerated. our relationships with our partners were strained. many questioned whether america would or even could lead again. a few guiding premises this year one is that american engagement american leadership matters. the word -- the world doesn't organize itself. we are not engaged, or we don't lead, one of two things happen. either some other country tries to take our place, but not the way that advances our interests and values. or no one does. and then you get chaos. either way, it doesn't serve the american people. another ms is finding new ways to